Efavirenz / Sustiva

Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS.

Efavirenz, sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlestick injury or other potential exposure.

Wikipedia

Side Effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).


Common side effects may include:

- nausea, vomiting;
- dizziness, drowsiness, trouble concentrating;
- rash;
- headache, tired feeling;
- sleep problems (insomnia), strange dreams; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

The recommended adult dosage of Sustiva (Efavirenz) is 600 mg orally, once daily, in combination with a protease inhibitor and/or nucleoside analogue reverse transcriptase inhibitors (NRTIs). Sustiva may interact with cyclosporine, itraconazole, sirolimus, tacrolimus, St. John's wort, voriconazole, blood thinners, cholesterol medications, antibiotics, heart or blood pressure medications, other HIV medicines, or seizure medications. Tell your doctor all medications you use. Sustiva is not recommended for use during pregnancy. It may harm a fetus, especially if taken during the first 3 months of pregnancy. Women of childbearing age should have a pregnancy test before starting this medication. Consult your doctor about using at least 2 forms of birth control (such as condoms with birth control pills) during treatment and for 3 months after the end of treatment. If you become pregnant or think you may be pregnant, tell your doctor immediately. It is unknown if Sustiva passes into breast milk. Because breast milk can transmit HIV, do not breastfeed.